Bio x4 Review 2018: Ingredients, Results, Side Effects, Where To Buy It & Best Alternative

In this article (Last Update 2018) we will explain to you what is Nucific Bio x4, how does it work, what are its ingredients, side effects, show you real customer reviews, give you prices, where to buy it & recommend best alternative.

biox4 photo

Excess weight in the body can be harmful to a person’s health. Obesity causes many health risks, such as diabetes, hypertension, heart disease, dyslipidemia, cerebrovascular disease, pulmonary abnormalities, and metabolic syndrome.

Weight loss is difficult when cravings and binge eating becomes a problem. Many people find it difficult to control these cravings, causing them to overeat. The result is weight gain instead of weight loss.

Many products have been introduced to help individuals burn fat and speed up their metabolism in the past. In this post, we want to look at the Bio X4 multi-action formulation from the Nucific brand.

What Is Bio X4

Bio X4 is a very unique weight management supplement – with an emphasis on the “management” part. This is not just a product that helps to speed up weight loss, but also provides a way for a healthy weight to be maintained.

This supplement goes far beyond what we are used to seeing in weight loss supplements. It does not only focus on burning fat and suppressing appetite but also attends to digestive well-being. The result is a healthier overall feeling.

The manufacturer of this product is Nucific. This brand has become quite popular in the supplements industry lately. They manufacture a wide range of different supplements that include 100% natural ingredients with no fillers and no harmful chemical compounds.


nucific bio x4 label

The most impressive feature of Bio X4 is likely to be the fact that the product offers a unique approach to weight loss, as well as to weight management.

Instead of focusing on providing specific functions that are often useless when it comes to taking a supplement to boost weight loss results, this formula includes four different proprietary blends that all work together in good harmony to deliver potent results – in a healthy way.

Let’s look at each of the proprietary blends that are included in this supplement.

Probiotic Blend

A unique blend of probiotics to help balance the gut flora of the user.

  • Lactobacillus Blend (L. acidophilus, L. rhamnosus, L. plantarum)
  • Bifidobacterium Blend (B. lactis, B. animalis)

Digestive Enzyme Blend

A collection of enzymes that are known to provide improvements in digestive function and the processing of food throughout the gastrointestinal tract.

  • Amylase
  • Bromelain
  • Lipase

Weight Management Blend

A blend that helps to speed up the rate at which the user burns fat – not only while participating in an exercise, but even at rest.

  • Green Tea Extract with 50% EGCG concentration.

Craving Control Blend

A unique, powerful blend that helps to reduce cravings and daily total caloric intake to address one of the most common problems among individuals who struggle to lose weight.

  • Caralluma Fimbriata Extract

How Does It Work

Binge eating is one of the most common problems today that causes people to gain excess weight. This issue also makes it much harder for total body weight to be reduced effectively.

Bio X4 mainly acts upon curbing cravings in the user. The powerful ingredients help to eliminate cravings for fast foods and other unhealthy options. The product also includes ingredients that boost metabolism and helps to speed up fat loss.

In addition to a variety of weight loss ingredients, this supplement also utilizes a unique blend of both digestive enzymes and probiotics. The result of these substances is a healthier stomach that is more regular and gives fewer problems. In turn, this can nurture a better sense of wellbeing in the user.

How To Use It For Maximum Results

how to use bio x4

Even though the physiological actions behind the Bio X4 formula may seem very complications, existing users find it very easy to take advantage of this supplement and achieve impressive results in the shortest amount of time possible.

The best news is… there is no need for a person to go through any dramatic lifestyle changes if they wish to achieve success in their weight loss goals by implementing this supplement into their weight management plan.

When opting for this supplement, the user needs to ensure they follow the dosage guidelines to ensure they can benefit from the product, but also to avoid overdosing.

Most people who use this supplement find that three capsules daily give them excellent results. The three capsules should be split into three doses. One capsule before every meal of the day (breakfast, lunch, and dinner).

Some users might want to increase their dosage to experience more benefits. The maximum number of capsules that may be taken on any given day is six. This means a user can opt to take two capsules three times each day – again, two capsules before every meal.

For best results with Bio X4, users are advised to use the supplement along with an effective weight management plan. Even though these capsules contain many potent and useful ingredients, they will work more effectively when the right balance is found between food consumption and physical exercise.

Ideally, a weight management plan implement should consist of physical exercises that will ensure the user is able to exert a higher level of calories each day than what they take in.

In reality, this is the most effective way in which weight can be reduced at an optimal rate – and the ingredients found in this supplement have all been chosen based on their ability help the user achieve these goals.

One study provided a complete overview of how diet and exercise are both needed to benefit bodyweight, as well as that this combination yield positive results in both obese and overweight individuals.

Does It Cause Any Side Effects?

side effects

A particularly interesting fact about this supplement is that the manufacturer does not only focus on providing users with details on the ingredients. They also place emphasis on the particular ingredients they avoid using in the supplement.

This is good because there are some people they may experience allergic or sensitive reactions to the inclusions of certain inactive ingredients in this type of supplement.

According to the brand’s official website, the capsules do not contain any lactose and are made from vegetarian capsules. This makes the product suitable for individuals who are lactose intolerant, as well as for vegetarians and vegans.

The brand also explains that the capsules do not contain any type of fillers and that all ingredients are 100% pure. What this essentially means is that no substances have been added for “bulking up” the formula – instead, all that is found in these capsules are the ingredients listed on its label.

Still, users should be aware of the fact that they might experience some level of abdominal discomfort when they initiate the use of the supplement. These side-effects are usually very mild and tend to ease up rather quickly.

No serious concerns have been raised regarding the use of this supplement. Potential users should, however, take a look at the ingredient list and ensure they are not allergic or sensitive to any of the ingredients found in its formula.

Individuals currently taking prescription or over-the-counter medication should also consider getting in touch with their physician. Discussing the use of these drugs with the Bio X4 supplement will help them understand if the substances may interact with each other.

Is It A Scam?

In the modern world, we are faced with thousands of scams every single day. This makes it difficult to determine which brands to trust and which ones to steer clear from.

Luckily, we have done some research on the Nucific brand and the Bio X4 supplement in particular and found that this is most certainly not a scam.

The product is delivered promptly to customers, and it provides the actions described on its official website. A high-grade SSL certificate protects the brand’s website, and they keep all customer data secure and confidential.

Nucific Bio x4 Customer Reviews & Complaints


After extensively researching this product, we could not find any serious complaints from previous customers about the formula.

The only negative attribute that was reported about Nucific’s Bio X4 was the fact that some users tend to experience some discomfort in their digestive system at the beginning – this tends to clear away quickly once the natural flora of the gut has been restored.

We were able to find a lot of good comments about the product. What we did notice is that even the elderly are relying on this supplement – not only for weight loss but also for improving gut health and their general well-being.

Take a look at this review, for example:

My husband is a new person. He’s always had digestive problems since childhood. Very slow elimination. Now he goes daily like clockwork. He’s 71!

Another customer had this to say:

It definitely has cut my food cravings and given me more energy. I am digesting so much better with this, and I have a good deal of digestive issues. Thank you! I will be ordering more for sure.

A.R. Garcia:

I was apprehensive at first and the first week was intense. However, I haven’t felt this wonderful in a long time. All I can recommend is to give it a try, and you have nothing to lose. I mean a full refund, come on you will notice a difference!

These are just some of the reviews left behind after the product helped thousands of people make a positive change in their life.

Video Testimonial

Packages, Prices & Where To Buy It

nucific official

We’ll have to admit to one thing here – Bio X4 is most certainly not the cheapest weight loss supplement on the market. This does not, however, mean it is not worth the money.

The unique four-phase approach to weight loss and health management introduced by this supplement is what makes it worth buying and trying.

Each bottle of Nucific’s Bio X4 weight loss supplements come with 90 capsules, which is an adequate supply of the product for 30 days. Individuals who wish to take a stronger dose will have to buy two bottles each month as they will need to take 180 capsules every 30 days.

Here is an overview of the packages offered by the brand:

  • 1 Bottle (1-Month Supply): $99.00
  • 3 Bottles (3-Month Supply): $261.36 (Total savings: 12%)
  • 6 Bottles (6-Month Supply): $487.08 (Total savings: 18%)

This product can be purchased at the official website of its manufacturer:

It does not seem like the supplement is available from Amazon and interested customers should not expect to pick up a bottle of this product from a local store that specializes in supplements.

It does not seem like the brand allows for wholesalers to stock the product, but rather chooses to sell their supplements directly to the public.

Money Back Guarantee & Refund Policy

Nucific is so sure that this supplement will work for individuals interested in adding it to their weight loss plant hat they have introduced a 90-day full money-back guarantee. This gives customers a 90-day risk-free period to try the product and see if it will work for them.

If the user finds that they are not really seeing any difference in their weight or feeling healthier in their gut within the first three months of using this supplement, they can request a refund. Nucific explains that they will not ask any questions and will provide the customer with a refund upon their request.

Pros & Cons


  • The supplement can be introduced into a weight management plan without requiring any dramatic changes to the user’s current lifestyle.
  • There is no need to follow a diet that places a significant restriction on the daily caloric intake with this supplement.
  • The four-phase formula of this product addresses more than just the metabolism – it helps to create a better level of overall wellbeing for the user.
  • Effectively curbs cravings to ensure the user can avoid binge eating during the day and overeating during any of their three main meals.


  • Definitely not the cheapest on the market at just below $100 for single month’s supply.
  • Users who want to take the stronger dose will have to pay almost $200 on a monthly basis for the supplement.
  • May cause the user to experience some mild side-effects with their digestive system when starting out with the supplement.

Final Verdict

final verdict

Losing weight can be difficult, but it is certainly not impossible. With the right weight management plan and a supplement to support that weight loss goal, results can be achieved quickly and more conveniently.

Bio X4 from Nucific is an original product that cannot be found elsewhere. Its unique take on weight loss has made it stand out from most other weight loss supplements on the market. Not only is this supplement effective, but it is also deemed safe.

This product goes far beyond weight loss through its unique four-phase approach to better weight management. Customers only have good things to report after using this supplement, ranging from lower body weights all the way to impressive improvements in gastrointestinal health.

Review Date
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Bio x4
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48 thoughts on “Bio x4 Review 2018: Ingredients, Results, Side Effects, Where To Buy It & Best Alternative”

  1. Richard says:

    I have found this product to be beneficial. My digestive system is more efficient then before, and I do have some loss of appetite. Two weeks into using it, I give it a thumbs up!

  2. Kelly Williams says:

    I silly act disease and I wake up everyday just begging for energy cannot seem to eat anything that doesn’t make me feel bad my medicine that I take makes me feel bad and I started taking bio X4 and I just seem to have a little bit more energy I can’t digest food better and I’m not just eating anything I want I’m eating what I need to maintain a healthy diet I’m so happy I can’t say it enough if dr. Lee called me right now I would tell her thank you thank you thank you I am a very sick person but I’m not anymore thank you and I even had breast cancer and I can say that everything they gave me through all of the medicines and stuff this has made me feel better than I could ever expect better than I ever expected

    1. Brooke says:

      Did you take it while having breast cancer? One of the biggest issues I am dealing with right now, doing chemo, is that my stomach is just so screwed up. No nausea, just diarrhea. I didn’t know if you took this while doing chemo if it was more beneficial to you?

  3. Judy kramps says:

    I just saw a video on Facebook about BIO-X4. I thought I might try it, but the video never showed me how to do that . Plus-and this would be a determining factor of buying the product. The cost was 49.99 and the price would always be $49.99. So please let me know if I can buy it for that price now and in the future. Judy L K

    1. Naomi Benson says:

      Hi there Judy,

      Naomi here with Nucific. I am happy to hear that you are interested in trying our top selling product, BIO X4. I would be more than happy to assist you with your purchase. Please send me an email at so that I can further assist you with this. I look forward to hearing from you Judy. Thank you.

  4. Lesley says:

    This product caused me a lot of discomfort and the bloating was excessive. The bloating is what curbed my appetite and not what was in the product. It turned my system into a blocked and semi constipated state, not exactly what one of their claims is. It made me uncomfortable and feel ill and I had to be off of it at least a week before my system returned to normal. I messaged Dr. Amy Lee about it for feedback and the response I got, and I am not unaware that she is most likely NOT the one responding, was to call customer service about my next step. It’s been over 90 days so they are going in the trash.

    1. Naomi Benson says:

      Hi there Lesley,

      Naomi here with Nucific. I am sorry to hear that you did not have a good experience while taking BIO X4. While many of our customers see incredible results from using this product, supplements do not work the same for everyone. I would be more than happy to issue you a full refund just for giving BIO X4 a fair trial. Please email me directly at so that I can ensure you receive your refund as quickly as possible. Thank you Lesley.

    2. Deborah says:

      This is exactly what has happen

  5. Pat Ward says:

    I bought 1 bottle of Bio X4 about 6 weeks abo. At first, I liked it, as it made it seem easier to have bowel movements. I didn’t take 3 pills a day just 2, then toward the end just one a day. Toward the end of about 6 weeks of taking this product,my system is all messed up. I have constant gas and loose bowls. I have to run to the bathroom at least 15 – 20 times a day. I have been off the pills for over a week and its getting worse. I also have stomach cramping and headaches every day. I never had headaches before. I wish I had never started this medication. I don’t know when or if my system will ever get back to normal. Pat

    1. Rosanne Rogers says:

      I agree with every comment from Pat Ward. I have the same EXACT health issues

  6. richard says:

    I agree that digestion is essential to good health but after reading many reviews about this product, I feel that the money spent would not achieve the desired results that this video and product promises. I’m very confused about it and have decided to continue researching this problem.

  7. blake marley says:

    This pills are great…. I take two huge bowel movements everyday. I was always having constipation problems before biox4. Its been a month ive lost ten pounds. I didn’t change my lifestyle. Iam a biox4 customer for life. The American diet is horriable …. we need all the help we can get. Thank you nucific from the bottom of my heart.

  8. Lauren says:

    I’ve been taking Bio X4 for the past two weeks and am very happy with the product and my own change in behavior. The product recommends taking the pill five minutes before meals with water. That one step alone forces me to drink more water AND to make me more conscious about what I’m about to eat. This has helped me ask myself, “does what I’m about to it bring more energy or is it wasted?” The shift is what I believe we produce long term changes in my eating habits.
    I’ve also had less craving between meals; I don’t desire to snack all day or keep eating just to clear my plate. Furthermore, my digestion has been the best it has ever been.
    The combination of changes in attitude, drinking more water, adjusting my mindset before and during meals, better digestion, and less craving….well, I am a happy camper. I would totally recommend giving this product a try for at least a month.

  9. Debra Thomas says:

    Is Bio-x safe for coustomer with one kidney or with kidney disease .

  10. Gina O. says:

    So have a military discount?

  11. Briana says:

    Hi! I saw the video and am extremely interested. My only question is if it safe while nursing 2 times a day? Thanks

  12. Candy says:

    I haven’t read any reviews of people who have taken this for more than 6 weeks. Is Bio X4 something you take long term? Will I have to take it until my desired weight is reached? And will it work for people who have more then 100 pounds to lose? Also, I suffer from IBS. Will this aggravate it more or help it? Thank you for your time. I look forward to your response.

  13. Michelle Taylor Frazier says:

    I watched the video and would like to order the product today but it didn’t give any opportunity for it.

  14. MICHELLE DANAO says:

    Is this safe for a person with diabetes?

  15. Lori says:

    I planned on ordering 3 bottles so when I went to check it it begged me to order more or I’d never get another chance for this low price! This angered me so I’m not ordering any

    1. Shelly Bell says:

      I began using Biox4 in 2016. I ordered 6 bottles for $240. Since I discovered it works great for me if I take 1 pill, first thing in the am, every other day – I just today (2.20.18) went to the Nucific website to get a current price and it is STILL 6 bottles for $240.

  16. Karen Raimer says:

    I was hopeful that Bio- X4 would help my digestive problems but I get heartburn every time I take a pill requiring antacids and I have had watery diarrhea since starting 3 days ago. I will not be able to take them any longer. I hope I can get a refund.

  17. Sam says:

    So, the Bio X4 video recommends their pills along with eating less and healthier, regular exercise, and to give it about 1 to 2 months… PLEASE, READ ABOVE AND THINK…YOU ALL DO REALIZE WHAT MAKES YOU (OR WILL MAKE YOU) LOSE WEIGHT AND FEEL BETTER IS THE EATING LESS AND HEALTHIER, AND THE EXERCISE (HOWEVER LITTLE YOU DO), NOT THE PILLS.

  18. Monica says:

    I had my thyroid removed last year and I’m on synthyroid I started gaining weight and I’m very bloated . I decided to order a bottle today to see if it will help me.

  19. Rhonda says:

    So I started taking Bio X4 last week and since I have broke out with hives all over my body. Is there something in it that I could be allergic too. Taking that pill is the only thing I’ve done different, so that has to be it.

  20. Alfred E. Gratrix Sr says:

    I purchased your product and received it on the 23rd of January, started the suggested dosage on the 24th. of January. I have not lost one pound since this time. I quess it just doesn’t work for me and I want my money back as you quarante. Order # 288990767 consisted of 3 bottles of Bio-X4 at $89.84 and one bottle of Move 260 at $89.82 for a total of $179.66 to be returned. Please forward shipping instructions and prepaid postage ASAP.

    1. Blue says:

      LOL! You do realize this is not where you post that lol. This is just a website that decided to reciew the product.
      Also, yiu should take it for the reccomended time 1-*”2″* month’s to see results. Js

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